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2024

    Mazumder, D., Kholiqov, O., & Srinivasan, V.J. (2024) “Interferometric near-infrared spectroscopy (iNIRS) reveals that blood flow index depends on wavelength,” Biomedical Optics Express 15, 2152-2174 (link)

    2024

      Zhao, M., Zhou, W., Aparanji, S., Mazumder, D., & Srinivasan, V.J. (2023) “Interferometric diffusing wave spectroscopy imaging with an electronically variable time-of-flight filter,” Optica 10, 42-52 (link)

        Gupta, A.K. Meng, R., Modi, Y.S., and Srinivasan, V. J. (2023) “Imaging human macular pigments with visible light optical coherence tomography and superluminescent diodes,” Opt. Lett. (link)

          Chauhan, P., Kho, A. M., & Srinivasan, V. J. (2023) “From soma to synapse: imaging age-related rod photoreceptor changes in the mouse with visible light optical coherence tomography.”Ophthalmology Science (link)

            Aparanji, S., Zhao, M., & Srinivasan, V.J. (2023) “Decoding diffuse light scattering dynamics in layered tissues: path length versus fluctuation time scale,” Opt. Lett. (link)

             

            2022

              Taliaferro, A.S., Fayed, M.A., Tsikata, E., De Luna, R.A., Jassim, F., Pandit, S., Park, E.A., Guzman Aparicio, M.A., Poon, L.Y., Que, C., Simavli, H., Srinivasan, V., de Boer, J.F., Chen, T.C. Facilitating glaucoma diagnosis with inter-eye neuroretinal rim asymmetry analysis using spectral domain optical coherence tomography. Digit J Ophthalmol. December 26, 2022. (link)

              Zhou, W., Zhao, M., Srinivasan, V. J., “Interferometric diffuse optics: recent advances and future outlook,” Neurophotonics 10(1) 013502 (link)

              Kholiqov, O., Zhou, W., Zhang, T., Zhao, M., GhandiParsi, S., & Srinivasan, V.J. (2022). Scanning interferometric near-infrared spectroscopy (iNIRS) for three-dimensional imaging of adult human forehead blood flow.  Optics Letters 47(1), 110-113. (link)

              Abdelfattah, A. S., Ahuja, S., Akkin, T., Allu, S. R., Brake, J., Boas, D. A., Buckley, E. M., Campbell, R. E., Chen, A. I., Cheng, X., Cizmar, T., Costantini, I., De Vittorio, M., Devor, A., Doran, P. R., El Khatib, M., Emiliani, V., Fomin-Thunemann, N., Fainman, Y., Fernandez-Alfonso, T., Ferri, C. G. L., Gilad, A., Han, X., Harris, A., Hillman, E. M. C., Hochgeschwender, U., Holt, M. G., Ji, N., Kilic, K., Lake, E. M. R., Li, L., Li, T., Machler, P., Miller, E. W., Mesquita, R. C., Nadella, K., Nagerl, U. V., Nasu, Y., Nimmerjahn, A., Ondrackova, P., Pavone, F. S., Perez Campos, C., Peterka, D. S., Pisano, F., Pisanello, F., Puppo, F., Sabatini, B. L., Sadegh, S., Sakadzic, S., Shoham, S., Shroff, S. N., Silver, R. A., Sims, R. R., Smith, S. L., Srinivasan, V. J., Thunemann, M., Tian, L., Tian, L., Troxler, T., Valera, A., Vaziri, A., Vinogradov, S. A., Vitale, F., Wang, L. V., Uhlirova, H., Xu, C., Yang, C., Yang, M. H., Yellen, G., Yizhar, O. & Zhao, Y. (2022). Neurophotonic tools for microscopic measurements and manipulation: status report. Neurophotonics 9, 013001. (link)

              Ayaz H., Baker W.B., Blaney G., Boas D.A., Bortfeld H., Brady K., Brake J., Brigadoi S., Buckley E.M., Carp S.A., Cooper R.J., Cowdrick K.R., Culver J.P., Dan I., Dehghani H., Devor A., Durduran T., Eggebrecht A.T., Emberson L.L., Fang Q., Fantini S., Franceschini M.A., Fischer J.B., Gervain J., Hirsch J., Hong K.S., Horstmeyer R., Kainerstorfer J.M., Ko T.S., Licht D.J., Liebert A., Luke R., Lynch J.M., Mesquida J., Mesquita R.C., Naseer N., Novi S.L., Orihuela-Espina F., O’Sullivan T.D., Peterka D.S., Pifferi A., Pollonini L., Sassaroli A., Sato J.R., Scholkmann F., Spinelli L., Srinivasan V.J., St Lawrence K., Tachtsidis I., Tong Y., Torricelli A., Urner T., Wabnitz H., Wolf M., Wolf U., Xu S., Yang C., Yodh A.G., Yucel M.A., Zhou W. Optical imaging and spectroscopy for the study of the human brain: status report. Neurophotonics. 2022;9 (Suppl 2):S24001. Epub 2022/09/03. doi: 10.1117/1.NPh.9.S2.S24001. (link)

              Chauhan P., Kho A.M., FitzGerald P., Shibata B., & Srinivasan V.J. (2022) Subcellular Comparison of Visible-Light Optical Coherence Tomography and Electron Microscopy in the Mouse Outer Retina. Invest Ophthalmol Vis Sci. 63(9):10. doi: 10.1167/iovs.63.9.10. PMID: 35943734. (link)

              Srinivasan, V.J.,  Kho, A.M., & Chauhan P. (2022). Visible Light Optical Coherence Tomography Reveals the Relationship of the Myoid and Ellipsoid to Band 2 in Humans. Trans. Vis. Sci. Tech. 11(9):3. (link)

              2021

                Kho, A., & Srinivasan, V.J. (2021). Proactive spectrometer matching for excess noise suppression in balanced visible light Optical Coherence Tomography (OCT). Optics Express, 29(25), 42037-42054. (link)

                Zhou, W., Zhao, M., Kholiqov, O., & Srinivasan, V.J. (2021). Multi-exposure interferometric diffusing wave spectroscopy. Optics Letters 46(18), 4498-4501. (link)

                Zhu, J., Freitas, H.R., Maezawa, I., Jin, L.W., & Srinivasan, V.J. (2021). 1700 nm optical coherence microscopy enables minimally invasive, label-free, in vivo optical biopsy deep in the mouse brain. Light: Science & Applications 10, 145. (link) (commentary) (popular articles)

                Beykin, G., Norcia, A. M., Srinivasan, V. J., Dubra, A., & Goldberg, J. L. (2021). Discovery and clinical translation of novel glaucoma biomarkers. Progress in Retinal and Eye Research, 100875. (link)

                Zhang, T., Kho, A.M., Yiu, G., & Srinivasan, V.J. (2021). Visible Light Optical Coherence Tomography (OCT) Quantifies Subcellular Contributions to Outer Retinal Band 4. Trans. Vis. Sci. Tech. 10(3):30. (link)

                Zhang, T., Kho, A.M., & Srinivasan, V.J. (2021). In vivo Morphometry of Inner Plexiform Layer (IPL) Stratification in the Human Retina With Visible Light Optical Coherence Tomography. Front. Cell. Neurosci. 15(655096), 1-13. (link)

                Zhou W., Kholiqov O., Zhu J., Zhao M., Zimmermann L.L., Martin R.M., Lyeth B.G., Srinivasan V.J. (2021). Functional interferometric diffusing wave spectroscopy of the human brain. Science Advances. 7(20). (link) (popular articles)

                2020

                Zhang, T., Kho, A.M., Zawadzki, R., Jonnal, R., Yiu, G., & Srinivasan, V.J. (2020). Visible light OCT improves imaging through a highly scattering retinal pigment epithelial wall. Optics Letters. 45, 5945-5948. (link)

                Kho, A.M., Zhang, T., Zhu, J., Merkle, C.W., & Srinivasan, V.J. (2020). Incoherent excess noise spectrally encodes broadband light sources. Light: Science & Applications 9, 172. (link) (popular articles)

                Zhang, T., Kho, A.M., & Srinivasan, V.J. (2020). Water wavenumber calibration for visible light optical coherence tomography. Journal of Biomedical Optics, 25(9), 090501. (link)

                Zhu, J., Bernucci, M. T., Merkle, C. W., & Srinivasan, V. J. (2020). Visibility of microvessels in Optical Coherence Tomography Angiography depends on angular orientation. Journal of Biophotonics, e202000090. (link)

                Fong, D.D., Yamashiro, J.K., Vali, K., … & Ghiasi, S. (2020). Design and In Vivo Evaluation of a Non-invasive Transabdominal Fetal Pulse Oximeter. IEEE Transactions on Biomedical Engineering. (link)

                Srinivasan, V. J., & Moshiri, A. (2020). Imaging oxygenation of retinal capillaries with depth resolution. Proceedings of the National Academy of Sciences, 117(26), 14626-14628. (link)

                Le, V.N.D., & Srinivasan, V.J. (2020). Beyond diffuse correlations: deciphering random flow in time-of-flight resolved light dynamics. Optics Express, 28(8), 11191-11214. (link)

                Kholiqov, O., Zhou, W., Zhang, T., Le, V.N.D., Srinivasan, V.J. (2020). Time-of-flight resolved light field fluctuations reveal deep human tissue physiology. Nature communications. 11, 391. (link)

                2019

                Fong, D.D., Srinivasan, V.J., Vali, K., & Ghiasi, S. (2019). Optode Design Space Exploration for Clinically-robust Non-invasive Fetal Oximetry. ACM Transactions on Embedded Computing Systems (TECS). 18(5s), 63. (link)

                Merkle, C.W., Zhu, J., Bernucci, M.T., & Srinivasan, V.J. (2019). Dynamic Contrast Optical Coherence Tomography reveals laminar microvascular hemodynamics in the mouse neocortex in vivo. Neuroimage. 202. 116067. (link)

                Zhu, J., Chong, S.P., Zhou, W., & Srinivasan, V.J. (2019). Noninvasive, in vivo rodent brain optical coherence tomography at 2.1 microns.  Optics Letters, 44(17), 4147-4150. (link). This paper is featured in Spotlight on Optics.

                Zhang, T., Kho, A.M., & Srinivasan, V.J. (2019). Improving visible light OCT of the human retina with rapid spectral shaping and axial tracking. Biomedical optics express, 10(6), 2918-2931. (link). This paper is featured as Editors’ Pick.

                Kho, A.M., & Srinivasan, V.J. (2019). Compensating spatially dependent dispersion in visible light OCT. Optics letters, 44(4), 775-778. (link) This paper is featured in Spotlight on Optics.

                2018

                Borycki, D., Kholiqov, O., & Srinivasan, V.J. (2018). Correlation gating quantifies the optical properties of dynamic media in transmission. Optics letters, 43(23), 5865-5868. (link)

                Zhou, W., Kholiqov, O., Chong, S.P., & Srinivasan, V.J. (2018). Highly parallel, interferometric diffusing wave spectroscopy for monitoring cerebral blood flow dynamics. Optica, 5(5), 518-527. (link) (see popular articles in Optics and Photonics NewsBioOptics World, Science & Enterprise, and Physics.Org)

                Chong, S.P*., Zhang, T*., Kho, A.M., Bernucci, M.T., Dubra, A., & Srinivasan, V.J. (2018). Ultrahigh resolution retinal imaging by visible light OCT with longitudinal achromatization. Biomedical optics express, 9(4), 1477-1491. (link)

                Campagnola, P., Cote, D., Pavone, F., Reece, P., Srinivasan, V.J., Tkaczyk, T., & Volpe, G. (2018). Biophotonics feature: introduction. Biomedical optics express, 9(3), 1229-1231. (link)

                Bernucci, M.T., Merkle, C.W., & Srinivasan, V.J. (2018). Investigation of artifacts in retinal and choroidal OCT angiography with a contrast agent. Biomedical optics express, 9(3), 1020-40. (link). This paper is featured as Editors’ Pick.

                Merkle, C.W., Chong, S. P., Kho, A. M., Zhu, J., Dubra, A., & Srinivasan, V.J. (2018). Visible light optical coherence microscopy of the brain with isotropic femtoliter resolution in vivo. Optics Letters43(2). (link).

                2017

                Kholiqov, O., Borycki, D., & Srinivasan, V.J. (2017). Interferometric near-infrared spectroscopy (iNIRS): performance tradeoffs and optimization. Optics Express25(23). (link).

                Zhu, J., Merkle, C.W., Bernucci, M.T., Chong, S.P., & Srinivasan, V.J.  (2017). Can OCT Angiography Be Made a Quantitative Blood Measurement Tool? Applied Sciences, 7(687). (link). This review paper is featured on the cover of Applied Sciences.

                Borycki, D., Kholiqov, O., & Srinivasan, V. J. (2017). Reflectance-mode interferometric near-infrared spectroscopy quantifies brain absorption, scattering, and blood flow index in vivo. Optics letters, 42(3), 591-594. (link).

                Chong, S. P., Bernucci, M., Radhakrishnan, H., & Srinivasan, V. J. (2017). Structural and functional human retinal imaging with a fiber-based visible light OCT ophthalmoscope. Biomedical Optics Express, 8(1), 323-337. (link).

                2016

                Wang, M., Norman, J. E., Srinivasan, V. J., & Rutledge, J. C. (2016). Metabolic, inflammatory, and microvascular determinants of white matter disease and cognitive decline. American Journal of Neurodegenerative Disease, 5(5), 171. (link)

                Borycki, D., Kholiqov, O., & Srinivasan, V. J. (2016). Interferometric near-infrared spectroscopy directly quantifies optical field dynamics in turbid media. Optica, 3(12), 1471-1476. (link)

                Srinivasan, V. J., & Dubra, A. (2016). Noninvasive imaging of the photoreceptor mosaic response to light stimulation. Proceedings of the National Academy of Sciences, 113(46), 12902-12903. (link)

                Merkle, C. W., Leahy, C., & Srinivasan, V. J. (2016). Dynamic contrast optical coherence tomography images transit time and quantifies microvascular plasma volume and flow in the retina and choriocapillaris. Biomedical Optics Express, 7(10), 4289-4312. (link)

                Goergen, C. J., Chen, H. H., Sakadžić, S., Srinivasan, V. J., & Sosnovik, D. E. (2016). Microstructural characterization of myocardial infarction with optical coherence tractography and two‐photon microscopy. Physiological Reports, 4(18), e12894. (link)

                Shieh, E., Lee, R., Que, C., Srinivasan, V., Guo, R., DeLuna, R., … & Chen, T. C. (2016). Diagnostic Performance of a Novel Three-Dimensional Neuroretinal Rim Parameter for Glaucoma Using High-Density Volume Scans. American Journal of Ophthalmology, 169, 168-178. (link)

                Leahy, C., Radhakrishnan, H., Bernucci, M., & Srinivasan, V. J. (2016). Imaging and graphing of cortical vasculature using dynamically focused optical coherence microscopy angiography. Journal of biomedical optics, 21(2), 020502-020502. (link)

                Borycki, D., Kholiqov, O., Chong, S. P., & Srinivasan, V. J. (2016). Interferometric Near-Infrared Spectroscopy (iNIRS) for determination of optical and dynamical properties of turbid media. Optics express, 24(1), 329-354. (link)

                Merkle, C. W., & Srinivasan, V. J. (2016). Laminar microvascular transit time distribution in the mouse somatosensory cortex revealed by Dynamic Contrast Optical Coherence Tomography. Neuroimage, 125, 350-362. (link).

                2015

                Yaseen, M. A., Srinivasan, V. J., Gorczynska, I., Fujimoto, J. G., Boas, D. A., & Sakadžić, S. (2015). Multimodal optical imaging system for in vivo investigation of cerebral oxygen delivery and energy metabolism. Biomedical optics express, 6(12), 4994-5007. (link)

                Chong, S. P., Merkle, C. W., Cooke, D. F., Zhang, T., Radhakrishnan, H., Krubitzer, L., & Srinivasan, V. J. (2015). Noninvasive, in vivo imaging of subcortical mouse brain regions with 1.7 μm optical coherence tomography. Optics letters, 40(21), 4911-4914. (link). This paper is featured in Spotlight on Optics.

                Srinivasan, V. J., Yu, E., Radhakrishnan, H., Can, A., Climov, M., Leahy, C., … & Eikermann-Haerter, K. (2015). Micro-heterogeneity of flow in a mouse model of chronic cerebral hypoperfusion revealed by longitudinal Doppler optical coherence tomography and angiography. Journal of Cerebral Blood Flow & Metabolism. (link). Our paper was featured on the Cover Photo of the October Issue.

                Chong, S. P., Merkle, C. W., Leahy, C., & Srinivasan, V. J. (2015). Cerebral metabolic rate of oxygen (CMRO 2) assessed by combined Doppler and spectroscopic OCT. Biomedical optics express, 6(10), 3941-3951. (link).

                Leahy, C., Radhakrishnan, H., Weiner, G., Goldberg, J. L., & Srinivasan, V. J. (2015). Mapping the 3D Connectivity of the Rat Inner Retinal Vascular Network Using OCT Angiography3D Graphing Based on OCT Angiography. Investigative ophthalmology & visual science, 56(10), 5785-5793. (link).

                Chong, S. P., Merkle, C. W., Leahy, C., Radhakrishnan, H., & Srinivasan, V. J. (2015). Quantitative microvascular hemoglobin mapping using visible light spectroscopic Optical Coherence Tomography. Biomedical optics express, 6(4), 1429-1450. (link).

                2014

                Sakadžić, S., Mandeville, E. T., Gagnon, L., Musacchia, J. J., Yaseen, M. A., Yucel, M. A., … & Boas, D. A. (2014). Large arteriolar component of oxygen delivery implies a safe margin of oxygen supply to cerebral tissue. Nature communications, 5. (link)

                Srinivasan, V. J., & Radhakrishnan, H. (2014). Optical Coherence Tomography angiography reveals laminar microvascular hemodynamics in the rat somatosensory cortex during activation. NeuroImage, 102, 393-406. (link). This study was featured on the OCT News website ‘Feature of The Week‘.

                Chan, A. C., Srinivasan, V. J., & Lam, E. Y. (2014). Maximum likelihood Doppler frequency estimation under decorrelation noise for quantifying flow in optical coherence tomography. IEEE transactions on medical imaging, 33(6), 1313-1323. (link)

                2013

                Leahy, C., Radhakrishnan, H., & Srinivasan, V. J. (2013). Volumetric imaging and quantification of cytoarchitecture and myeloarchitecture with intrinsic scattering contrast. Biomedical optics express, 4(10), 1978-1990. (link)

                Radhakrishnan, H., & Srinivasan, V. J. (2013). Multiparametric optical coherence tomography imaging of the inner retinal hemodynamic response to visual stimulation. Journal of biomedical optics, 18(8), 086010-086010. (link)

                Srinivasan, V. J., Mandeville, E. T., Can, A., Blasi, F., Climov, M., Daneshmand, A., … & Ayata, C. (2013). Multiparametric, longitudinal optical coherence tomography imaging reveals acute injury and chronic recovery in experimental ischemic stroke. PloS one, 8(8), e71478. (link). This study was featured on the OCT News website ‘Feature of The Week‘.

                Srinivasan, V. J., & Radhakrishnan, H. (2013). Total average blood flow and angiography in the rat retina. Journal of biomedical optics, 18(7), 076025-076025. (link)

                Radhakrishnan, H., & Srinivasan, V. J. (2013). Compartment-resolved imaging of cortical functional hyperemia with OCT angiography. Biomedical optics express, 4(8), 1255-1268. (link). This paper is featured in Spotlight on Optics.

                Chan, A. C., Lam, E. Y., & Srinivasan, V. J. (2013). Comparison of kasai autocorrelation and maximum likelihood estimators for Doppler optical coherence tomography. IEEE transactions on medical imaging, 32(6), 1033-1042. (link).

                2012

                Goergen, C. J., Radhakrishnan, H., Sakadžić, S., Mandeville, E. T., Lo, E. H., Sosnovik, D. E., & Srinivasan, V. J. (2012). Optical coherence tractography using intrinsic contrast. Optics letters, 37(18), 3882-3884. (link).

                Devor, A., Sakadžić, S., Srinivasan, V. J., Yaseen, M. A., Nizar, K., Saisan, P. A., … & Boas, D. A. (2012). Frontiers in optical imaging of cerebral blood flow and metabolism. Journal of Cerebral Blood Flow & Metabolism, 32(7), 1259-1276. (link).

                Srinivasan, V. J., Radhakrishnan, H., Lo, E. H., Mandeville, E. T., Jiang, J. Y., Barry, S., & Cable, A. E. (2012). OCT methods for capillary velocimetry. Biomedical optics express, 3(3), 612-629. (link).

                Srinivasan, V. J., Radhakrishnan, H., Jiang, J. Y., Barry, S., & Cable, A. E. (2012). Optical coherence microscopy for deep tissue imaging of the cerebral cortex with intrinsic contrast. Optics express, 20(3), 2220-2239. (link).

                Yuzawa, I., Sakadžić, S., Srinivasan, V. J., Shin, H. K., Eikermann-Haerter, K., Boas, D. A., & Ayata, C. (2012). Cortical spreading depression impairs oxygen delivery and metabolism in mice. Journal of Cerebral Blood Flow & Metabolism, 32(2), 376-386. (link).

                2011

                Baraghis, E., Bolduc, V., Lefebvre, J., Srinivasan, V. J., Boudoux, C., Thorin, E., & Lesage, F. (2011). Measurement of cerebral microvascular compliance in a model of atherosclerosis with optical coherence tomography. Biomedical optics express, 2(11), 3079-3093. (link).

                Baraghis, E., Devor, A., Fang, Q., Srinivasan, V. J., Wu, W., Lesage, F., … & Sakadžić, S. (2011). Two-photon microscopy of cortical NADH fluorescence intensity changes: correcting contamination from the hemodynamic response. Journal of biomedical optics, 16(10), 106003-106003. (link).

                Devor, A., Sakadžić, S., Saisan, P. A., Yaseen, M. A., Roussakis, E., Srinivasan, V. J., … & Boas, D. A. (2011). “Overshoot” of O2 is required to maintain baseline tissue oxygenation at locations distal to blood vessels. The Journal of Neuroscience, 31(38), 13676-13681. (link).

                Carp, S. A., Roche-Labarbe, N., Franceschini, M. A., Srinivasan, V. J., Sakadžić, S., & Boas, D. A. (2011). Due to intravascular multiple sequential scattering, diffuse correlation spectroscopy of tissue primarily measures relative red blood cell motion within vessels. Biomedical optics express, 2(7), 2047-2054. (link).

                Srinivasan, V. J., Atochin, D. N., Radhakrishnan, H., Jiang, J. Y., Ruvinskaya, S., Wu, W., … & Boas, D. A. (2011). Optical coherence tomography for the quantitative study of cerebrovascular physiology. Journal of Cerebral Blood Flow & Metabolism, 31(6), 1339-1345. (link).

                Sakadžić, S., Roussakis, E., Yaseen, M. A., Mandeville, E. T., Srinivasan, V. J., Arai, K., … & Vinogradov, S. A. (2011). Cerebral blood oxygenation measurement based on oxygen-dependent quenching of phosphorescence. JoVE (Journal of Visualized Experiments), (51), e1694-e1694. (link).

                Yaseen, M. A., Srinivasan, V. J., Sakadžić, S., Radhakrishnan, H., Gorczynska, I., Wu, W., … & Boas, D. A. (2011). Microvascular oxygen tension and flow measurements in rodent cerebral cortex during baseline conditions and functional activation. Journal of Cerebral Blood Flow & Metabolism, 31(4), 1051-1063. (link).

                Judson, C. H., Vuong, L. N., Gorczynska, I., Srinivasan, V. J., Fujimoto, J. G., & Duker, J. S. (2011). Intact retinal tissue and retinal pigment epithelium identified within a coloboma via high-speed, ultrahigh resolution optical coherence tomography. Retinal cases & brief reports, 5(1), 46. (link).

                2010

                Sakadžić, S., Roussakis, E., Yaseen, M. A., Mandeville, E. T., Srinivasan, V. J., Arai, K., … & Boas, D. A. (2010). Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue. Nature methods, 7(9), 755-759. (link).

                Srinivasan, V. J., Sakadžić, S., Gorczynska, I., Ruvinskaya, S., Wu, W., Fujimoto, J. G., & Boas, D. A. (2010). Quantitative cerebral blood flow with optical coherence tomography. Optics express, 18(3), 2477-2494. (link).

                Sull, A. C., Vuong, L. N., Price, L. L., Srinivasan, V. J., Gorczynska, I., Fujimoto, J. G., … & Duker, J. S. (2010). Comparison of spectral/Fourier domain optical coherence tomography instruments for assessment of normal macular thickness. Retina (Philadelphia, Pa.), 30(2), 235. (link).

                Srinivasan, V. J., Jiang, J. Y., Yaseen, M. A., Radhakrishnan, H., Wu, W., Barry, S., … & Boas, D. A. (2010). Rapid volumetric angiography of cortical microvasculature with optical coherence tomography. Optics letters, 35(1), 43-45. (link).

                2009

                Yaseen, M. A., Srinivasan, V. J., Sakadžić, S., Wu, W., Ruvinskaya, S., Vinogradov, S. A., & Boas, D. A. (2009). Optical monitoring of oxygen tension in cortical microvessels with confocal microscopy. Optics express, 17(25), 22341-22350. (link).

                Srinivasan, V. J., Sakadžić, S., Gorczynska, I., Ruvinskaya, S., Wu, W., Fujimoto, J. G., & Boas, D. A. (2009). Depth-resolved microscopy of cortical hemodynamics with optical coherence tomography. Optics letters, 34(20), 3086-3088. (link).

                Witkin, A. J., Vuong, L. N., Srinivasan, V. J., Gorczynska, I., Reichel, E., Baumal, C. R., … & Duker, J. S. (2009). High-speed ultrahigh resolution optical coherence tomography before and after ranibizumab for age-related macular degeneration. Ophthalmology, 116(5), 956-963. (link).

                Gorczynska, I., Srinivasan, V. J., Vuong, L. N., Chen, R. W., Liu, J. J., Reichel, E., … & Fujimoto, J. G. (2009). Projection OCT fundus imaging for visualising outer retinal pathology in non-exudative age-related macular degeneration. British Journal of Ophthalmology, 93(5), 603-609. (link).

                Srinivasan, V. J., Chen, Y., Duker, J. S., & Fujimoto, J. G. (2009). In vivo functional imaging of intrinsic scattering changes in the human retina with high-speed ultrahigh resolution OCT. Optics express, 17(5), 3861-3877. (link).

                Chen, Y., Vuong, L. N., Liu, J., Ho, J., Srinivasan, V. J., Gorczynska, I., … & Fujimoto, J. G. (2009). Three-dimensional ultrahigh resolution optical coherence tomography imaging of age-related macular degeneration. Optics express, 17(5), 4046-4060. (link).

                2008

                Srinivasan, V. J., Adler, D. C., Chen, Y., Gorczynska, I., Huber, R., Duker, J. S., … & Fujimoto, J. G. (2008). Ultrahigh-speed optical coherence tomography for three-dimensional and en face imaging of the retina and optic nerve head. Investigative ophthalmology & visual science, 49(11), 5103-5110. (link).

                Biedermann, B. R., Wieser, W., Eigenwillig, C. M., Palte, G., Adler, D. C., Srinivasan, V. J., … & Huber, R. (2008). Real time en face Fourier-domain optical coherence tomography with direct hardware frequency demodulation. Optics letters, 33(21), 2556-2558. (link).

                Potsaid, B., Gorczynska, I., Srinivasan, V. J., Chen, Y., Jiang, J., Cable, A., & Fujimoto, J. G. (2008). Ultrahigh speed spectral/Fourier domain OCT ophthalmic imaging at 70,000 to 312,500 axial scans per second. Optics express, 16(19), 15149-15169. (link).

                Gabriele, M. L., Ishikawa, H., Wollstein, G., Bilonick, R. A., Townsend, K. A., Kagemann, L., … & Schuman, J. S. (2008). Optical coherence tomography scan circle location and mean retinal nerve fiber layer measurement variability. Investigative ophthalmology & visual science, 49(6), 2315-2321. (link).

                Mumcuoglu, T., Wollstein, G., Wojtkowski, M., Kagemann, L., Ishikawa, H., Gabriele, M. L., … & Schuman, J. S. (2008). Improved visualization of glaucomatous retinal damage using high-speed ultrahigh-resolution optical coherence tomography. Ophthalmology, 115(5), 782-789. (link).

                Srinivasan, V. J., Monson, B. K., Wojtkowski, M., Bilonick, R. A., Gorczynska, I., Chen, R., … & Fujimoto, J. G. (2008). Characterization of outer retinal morphology with high-speed, ultrahigh-resolution optical coherence tomography. Investigative ophthalmology & visual science, 49(4), 1571-1579. (link).

                Chen, R. W., Gorczynska, I., Srinivasan, V. J., Fujimoto, J. G., Duker, J. S., & Reichel, E. (2008). High-speed ultrahigh-resolution optical coherence tomography findings in chronic solar retinopathy. Retinal cases & brief reports, 2(2), 103. (link).

                2007

                Witkin, A. J., Wojtkowski, M., Reichel, E., Srinivasan, V. J., Fujimoto, J. G., Schuman, J. S., & Duker, J. S. (2007). Photoreceptor disruption secondary to posterior vitreous detachment as visualized using high-speed ultrahigh-resolution optical coherence tomography. Archives of ophthalmology, 125(11), 1579-1580. (link).

                Yoon, M. K., Chen, R. W., Hedges, T. R., Srinivasan, V. J., Gorczynska, I., Fujimoto, J. G., … & Duker, J. S. (2007). High-speed, ultrahigh resolution optical coherence tomography of the retina in Hunter syndrome. Ophthalmic Surgery, Lasers and Imaging Retina, 38(5), 423-428. (link).

                Christopoulos, V., Kagemann, L., Wollstein, G., Ishikawa, H., Gabriele, M. L., Wojtkowski, M., … & Schuman, J. S. (2007). In vivo corneal high-speed, ultra–high-resolution optical coherence tomography. Archives of ophthalmology, 125(8), 1027-1035. (link).

                Kagemann, L., Wollstein, G., Wojtkowski, M., Ishikawa, H., Townsend, K. A., Gabriele, M. L., … & Schuman, J. S. (2007). Spectral oximetry assessed with high-speed ultra-high-resolution optical coherence tomography. Journal of biomedical optics, 12(4), 041212-041212. (link).

                Szkulmowski, M., Wojtkowski, M., Sikorski, B., Bajraszewski, T., Srinivasan, V. J., Szkulmowska, A., … & Kowalczyk, A. (2007). Analysis of posterior retinal layers in spectral optical coherence tomography images of the normal retina and retinal pathologies. Journal of biomedical optics, 12(4), 041207-041207. (link).

                Huber, R., Adler, D. C., Srinivasan, V. J., & Fujimoto, J. G. (2007). Fourier domain mode locking at 1050 nm for ultra-high-speed optical coherence tomography of the human retina at 236,000 axial scans per second. Optics letters, 32(14), 2049-2051. (link).

                Gabriele, M. L., Ishikawa, H., Wollstein, G., Bilonick, R. A., Kagemann, L., Wojtkowski, M., … & Schuman, J. S. (2007). Peripapillary nerve fiber layer thickness profile determined with high speed, ultrahigh resolution optical coherence tomography high-density scanning. Investigative ophthalmology & visual science, 48(7), 3154-3160. (link).

                Rodriguez-Padilla, J. A., Hedges, T. R., Monson, B., Srinivasan, V., Wojtkowski, M., Reichel, E., … & Fujimoto, J. G. (2007). High-speed ultra–high-resolution optical coherence tomography findings in hydroxychloroquine retinopathy. Archives of ophthalmology, 125(6), 775-780. (link).

                Kahook, M. Y., Noecker, R. J., Ishikawa, H., Wollstein, G., Kagemann, L., Wojtkowski, M., … & Schuman, J. S. (2007). Peripapillary schisis in glaucoma patients with narrow angles and increased intraocular pressure. American journal of ophthalmology, 143(4), 697-699. (link).

                Srinivasan, V. J., Huber, R., Gorczynska, I., Fujimoto, J. G., Jiang, J. Y., Reisen, P., & Cable, A. E. (2007). High-speed, high-resolution optical coherence tomography retinal imaging with a frequency-swept laser at 850 nm. Optics letters, 32(4), 361-363. (link).

                Gao, B. B., Clermont, A., Rook, S., Fonda, S. J., Srinivasan, V. J., Wojtkowski, M., … & Aiello, L. P. (2007). Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation. Nature medicine, 13(2), 181-188. (link).

                Monson, B. K., Greenberg, P. B., Greenberg, E., Fujimoto, J. G., Srinivasan, V. J., & Duker, J. S. (2007). High-speed, ultra-high-resolution optical coherence tomography of acute macular neuroretinopathy. British journal of ophthalmology, 91(1), 119-120. (link).

                2006

                Srinivasan, V. J., Ko, T. H., Wojtkowski, M., Carvalho, M., Clermont, A., Bursell, S. E., … & Fujimoto, J. G. (2006). Noninvasive volumetric imaging and morphometry of the rodent retina with high-speed, ultrahigh-resolution optical coherence tomography. Investigative ophthalmology & visual science, 47(12), 5522-5528. (link).

                Srinivasan, V. J., Wojtkowski, M., Witkin, A. J., Duker, J. S., Ko, T. H., Carvalho, M., … & Fujimoto, J. G. (2006). High-definition and 3-dimensional imaging of macular pathologies with high-speed ultrahigh-resolution optical coherence tomography. Ophthalmology, 113(11), 2054-2065. (link).

                Kagemann, L., Wollstein, G., Ishikawa, H., Gabriele, M. L., Srinivasan, V. J., Wojtkowski, M., … & Schuman, J. S. (2006). Persistence of Cloquet’s canal in normal healthy eyes. American journal of ophthalmology, 142(5), 862-864. (link).

                Srinivasan, V. J., Wojtkowski, M., Fujimoto, J. G., & Duker, J. S. (2006). In vivo measurement of retinal physiology with high-speed ultrahigh-resolution optical coherence tomography. Optics letters, 31(15), 2308-2310. (link).

                2005

                Wojtkowski, M., Srinivasan, V., Fujimoto, J. G., Ko, T., Schuman, J. S., Kowalczyk, A., & Duker, J. S. (2005). Three-dimensional retinal imaging with high-speed ultrahigh-resolution optical coherence tomography. Ophthalmology, 112(10), 1734-1746. (link).

                2004

                Wojtkowski, M., Srinivasan, V. J., Ko, T. H., Fujimoto, J. G., Kowalczyk, A., & Duker, J. S. (2004). Ultrahigh-resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation. Optics express, 12(11), 2404-2422. (link).

                POPULAR

                Spotlight Summary: Noninvasive, in vivo imaging of subcortical mouse brain regions with 1.7 μm optical coherence tomography. Spotlight on Optics (Optical Society of America, by Martin Villiger). 9/2015. (link)

                Catalyst for a Cure (The Biomarker Initiative). Glaucoma Research Foundation. (link)

                Simply shining a light can reveal the brain’s structure. Invited commentary for Scientific American MIND  Blog.  10/24/2014. (link)

                Spotlight Summary: High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s. Spotlight on Optics (Optical Society of America). 8/2014. (link)

                Precision-guided epidurals, better blood monitors for better care. Featured Research: The Optical Society Science Daily. 5/27/2014. (link)

                Novel Techniques for Measuring Capillary Blood Flow Using OCT. Thorlabs Application Article. (link)

                Absolute blood flow measured by optical methods. SPIE Newsroom, Biomedical Optics & Medical Imaging. 11/28/2011. (link)

                Spectral Domain OCT Employed to Study Cortical Microvasculature. Thorlabs Application Article. (link)

                Cerebral Blood Flow. Research Highlights, Nature Photonics. 4/2010. (link)

                Doppler optical coherence tomography for imaging of brain hemodynamics. SPIE Newsroom, Biomedical Optics & Medical Imaging. 7/6/2010. (link)

                Speed and Resolution Improve in Newest OCT. Review of Ophthalmology. 7/17/2007. (link)

                MIT team takes high-res, 3-D images of eye. MIT news (Elizabeth A. Thompson). 5/2/2007. (link)

                Advanced OCT opens way for 3-D retinal images. Ophthalmology Times (Lynda Charters). 8/15/2005. (link)

                BOOK CHAPTERS

                Leahy C, Srinivasan VJ. Three-Dimensional Optical Coherence Microscopy and Mapping of Angio-Architecture in the Central Nervous System. In: Chen Y, Kateb B, editors. The Textbook of Advanced Neurophotonics and Brain Mapping: CRC Press, Taylor and Francis Group; 2017.

                Radhakrishnan H, Franceschini MA, Srinivasan VJ. Neurovascular coupling investigated by simultaneous Optical Coherence Tomography and electrophysiology. In: Schwartz TH, editor. Neurovascular Coupling Methods. New York: Springer Science; 2013. p. 21-38.

                Srinivasan VJ, Chan AC, Lam EY. Doppler OCT and OCT Angiography for In Vivo Imaging of Vascular Physiology. In: Liu G, editor. Selected Topics Optical Coherence Tomography: InTech; 2011.

                 

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